wherabouts of spouse unknown for distribution of assets My husband’s father…

wherabouts of spouse unknown for distribution of assets
My husband’s father passed away. He was married but they have been seperated now for several months. We are unsure where she is now. Are there any legal issues my husband and his brother will run into? We have a copy of the will (is this is the up to date will) and she is not listed. There is land involved and a few assets (checking acct, savings acct, vehicles). My husband is listed as power of attorney in the will.